Polynucleotides
Polynucleotide Injections — Nucleofill / Plinest
Subtle, natural rejuvenation at the cellular level. Purified polynucleotides stimulate fibroblasts, boost collagen and elastin, and deeply hydrate the skin — delivering firmer, smoother, more radiant skin with minimal downtime and no “overfilled” look.
⸻
Why it Works
Biological Regeneration
Polynucleotides (highly purified DNA fragments) activate fibroblasts and skin repair pathways. This strengthens the dermal matrix, increases collagen and elastin production, and provides deep hydration.
⸻
Results
• Noticeable improvement in skin quality
• Refined texture and reduced fine lines
• Hydration “from within” without adding volume
⸻
Comfort
A typical session takes 20–40 minutes. Aside from temporary redness or small marks, most clients resume daily activities the same day.
⸻
Indications & Areas
We tailor concentration and technique to your skin’s needs — delicate eye area, face, neck/décolleté, hands, and supportive care for scalp.
Eye Area — Nucleofill Eyes
• Fine lines, under-eye shadows, delicate skin
• Protocol: 2 sessions 14 days apart; up to 4 in advanced cases
• Techniques: micro-injections (mesotherapy) or soft cannula
• Maintenance every 3–6 months
Face / Neck / Décolleté — Nucleofill Face
• Loss of elasticity, uneven texture, dehydration, oxidative stress
• Protocol: 2–4 sessions every 15–30 days
• Longevity: typically 6–12 months
• Techniques: lifting points, cannula fan, precision mesotherapy
Hair & Scalp — Nucleofill Hair
• Weakened follicles, early thinning, peri-transplant support
• Protocol: 4 sessions over several weeks + maintenance every ~2 months
• Can combine with PRP, mesotherapy, carboxytherapy, or light therapy
Plinest
• Polynucleotide booster ideal for sensitive areas (e.g., under eyes)
• Regenerative benefits similar to Nucleofill
• Selected during consultation for comfort and precision
⸻
Benefits
• Smoother, firmer, more radiant skin
• Deep, long-lasting hydration
• Improves skin quality without changing facial structure
• Minimal downtime and a natural look
• Suitable for men and women of all ages
⸻
Contraindications
Every treatment is preceded by a thorough medical history and eligibility check.
• Active skin infection or inflammation at the treatment site
• Known allergy to components (including fish-derived DNA)
• Pregnancy or breastfeeding
• Certain autoimmune conditions or bleeding disorders (assessed case-by-case)
• Recent dental procedures, vaccinations, or antibiotics — timing to be discussed
⸻
Possible Side Effects
Common & Temporary
• Redness, swelling, tenderness
• Mild bruising or small needle marks
• Slight itching or tightness
Rare
• Allergic reaction, infection, persistent lumps
• Prolonged swelling (especially around the eyes) — requires review
Red-flag symptoms: rapidly increasing pain or swelling, spreading redness/heat, fever, pus, breathing difficulty, or widespread rash — seek urgent medical attention.
⸻
Aftercare
First 24–48 hours
• Do not touch or massage treated areas; keep them clean
• Cold compresses (through a clean cloth) for swelling
• Avoid strenuous exercise, saunas, hot baths, and direct sun
• No makeup over treated areas for at least 24 hours
• Limit alcohol and blood-thinning medications if advised
Following days
• Daily SPF 30+ and gentle skincare
• Hydrate well — water intake supports results
• Avoid invasive procedures (peels/laser) for 1–2 weeks
• Attend follow-ups and maintenance as planned
⸻
Your Treatment Journey
1. Consultation — Skin analysis, medical history, and a personalised plan for Nucleofill or Plinest.
2. Procedure — Cleanse, disinfect, precise micro-injections or cannula delivery for comfort.
3. Aftercare — Clear guidance, scheduled sessions, and a maintenance plan for long-lasting results.
⸻
Safety
We operate to strict medical standards with on-site emergency protocols. All treatments are carried out by qualified professionals after informed consent and full eligibility screening.
⸻
FAQ
When will I see results?
Many clients notice improvement after the first session, but optimal results follow a full series of 2–4 treatments.
Is this the same as filler?
No. Polynucleotides are bio-stimulators — they trigger natural regeneration without adding volume.
Can it be combined with other treatments?
Yes. We often combine with PRP, LED light therapy, or other boosters. Your clinician will plan safe intervals.
How long do results last?
Typically 6–12 months, depending on age, skin condition, and maintenance.